Formulation–structure relationships
Particle size, dispersity, encapsulation, and stability are influenced by composition and the hydrodynamic conditions under which particles form.
Research
Advanced constructs at the biological interface.
Our research examines how formulation conditions, payload properties, lipid architecture, and surface chemistry influence biomolecular delivery.
Our approach
Solving the hardest problems in biomolecular delivery starts with a scalable, well-controlled foundation.
Ionisable lipid chemistry, ligand-mediated targeting, and advanced payload design can address established barriers in stability, tissue access, cellular uptake, and release. Translating those mechanisms into reliable delivery systems requires formulation and process engineering capable of preserving the intended molecular architecture.
Surface functionalisation
Ligand chemistry, density, orientation, and accessibility determine how a nanoparticle presents itself to its biological environment.
Payload compatibility
The size, charge, structure, and stability of a payload affect formulation behaviour, encapsulation, release, and process requirements.
Analytical control
Particle characterisation, composition, encapsulation, impurity measurement, and functional assays connect process settings to material performance.
From design to manufacture
A promising construct must remain controllable beyond the first formulation.
Biological performance alone is not enough. A delivery system must also withstand scale translation, material variability, downstream processing, storage, and the analytical demands required to understand it.
SC Biosystems connects molecular design with the microfluidic and process technologies needed to move advanced constructs towards repeatable manufacture.
Collaboration
Conversations across disciplines.
The difficult questions in biomolecular delivery span chemistry, formulation, instrumentation, analytics, and biology. Progress depends on clear communication across those boundaries.
We welcome relevant discussions with research organisations, technical partners, and specialist suppliers.
Contact our team ↗